Skip to main content

Clinical Trial Results

Search

Home Page

Editor in Chief – C. Michael Gibson

Follow on Twitter @CMichaelGibson

This Week in Cardiology

Dr. Michael Nanna and Dr. Gibson discuss the PERCISE trial. View Video

Guidelines for Atrial Fibrillation

Dr. DJ Lakkireddy and Dr. C Michael Gibson present: newest clinical guidelines released for preventing and optimally managing atrial fibrillation View Video

2023 in Prevention and Cardiometabolic Disease: The Year in Review

Dr. Pam Taub and Dr. C. Michael Gibson Present: Prevention and Cardiometabolic Disease 2023 Year in Review View Video

2023 in IC: The Year in Review 

Dr. Rasha Al-Lamee and Dr. C. Michael Gibson Present: An Interventional Cardiology 2023 Year in Review View Video

2023 in CHF: The Year in Review 

Dr. James Januzzi and Dr. C. Michael Gibson Present: A Heart Failure 2023 Year in Review View Video

Snackable Health

Dr. Harlan Krumholz shares vision for the Journal as the new Editor-in-Chief of JACC View Video

Dr. Manesh Patel and Dr. C. Michael Gibson Discuss: The early termination of the OCEANIC AF study of the Factor Xi Inhibitor Asundexian due to lack of efficacy View Video

AHA 2023

Dr. Paul Ridker and Dr. C. Michael Gibson Discuss: CLEAR OUTCOMES subanalysis on predicting CV events View Video | Download Slides

Dr. Richard Wright and Dr. C. Michael Gibson Discuss: The Genetic / Mendalian randomization (natures randomized trial) data that supports the efficacy of #Acoramadis in amyloidosis and the potential for amyloid regression with therapy View Video

Dr. Charalambos Antoniades and Dr. C. Michael Gibson Discuss: Novel AI Technology to Improve Risk Stratification of Patients Without Obstructive Coronary Artery Disease Undergoing CCTA: The Oxford Risk Factors and Non-Invasive Imaging (ORFAN) Study View Video

Dr. Demilade A Adedinsewo Presents: Screening for Peripartum Cardiomyopathies Using an Artificial Intelligence Enhanced Digital Stethoscope: A Randomized Clinical Trial Download Slides

Dr. Alexander Fanaroff Presents: A Cluster Randomized Trial of Automated Referral to Centralized Pharmacy Services for Evidence-Based Statin Initiation in High-Risk Patients Download Slides

Dr. Daniel Judge and Dr. C. Michael Gibson: Acoramidis from bench to bedside View Video

Dr. Steven Nissen and Dr. C. Michael Gibson Discuss: Efficacy and Safety of Lepodisiran: An Extended Duration Short-Interfering RNA Targeting Lipoprotein (a) View Video

Dr. Andrew Bellinger, Dr. Sek Kathiresan and Dr. C. Michael Gibson Discuss: Safety and Pharmacodynamic Effects of VERVE-101, an Investigational DNA Base Editing Medicine Designed to Durably Inactivate the PCSK9 Gene and Lower LDL Cholesterol – Interim Results of the Phase 1b heart-1 Trial View Video

Dr. Nina Becher and Dr. C. Michael Gibson Discuss: Efficacy and Safety of Anticoagulation With Edoxaban in Patients With AHRE Durations ≥24 Hours. The NOAH-AFNET 6 Trial View Video | Download Slides

Dr. Christian T Ruff and Dr. C. Michael Gibson Discuss: Abelacimab, a Novel Factor XI/XIa Inhibitor, vs Rivaroxaban in Patients with Atrial Fibrillation: Primary Results of the AZALEA-TIMI 71 Randomized Trial View Video | Download Slides

Dr. George Bakris and Dr. C. Michael Gibson Discuss: Sustained Blood Pressure Reduction With the RNA Interference Therapeutic Zilebesiran: Primary Results From KARDIA-1, a Phase 2 Study in Patients With Hypertension View Video | Download Slides

Dr. Mandeep Mehra and Dr. C. Michael Gibson Discuss: Avoidance of Aspirin With Left Ventricular Assist Devices in Advanced Heart Failure: Primary Results of the International, Double-Blind, Placebo-Controlled ARIES HM3 Clinical Trial View Video | Download Slides

Dr. Christopher Rajkumar, Dr. Rasha Al-Lamee and Dr. C. Michael Gibson Discuss: Percutaneous Coronary Intervention for Stable Angina (ORBITA-2): A Randomised, Placebo-Controlled Trial View Video

Dr. Jeffery Carson and Dr. Serge Korjian Discuss: Restrictive versus Liberal Blood Transfusion in Patients With Myocardial Infarction and Anemia: Results of the MINT Trial View Video | Download Slides

Dr. Stefan K. James Presents: DAPA-MI – A Registry-Based Randomized Trial of Dapagliflozin in Patients With Acute Myocardial Infarction Without Diabetes Download Slides

Dr. A. Michael Lincoff and Dr. C. Michael Gibson Discuss: Semaglutide and Cardiovascular Outcomes in Patients With Overweight or Obesity Who Do Not Have Diabetes View Video

An Obesity Town Hall 2023

Dr. C. Michael Gibson, Dr. Darren McGuire, Dr. Ildiko Lingvay, and Dr. Julio Rosenstock Discuss: An Obesity Town Hall: What’s Hot from Recent Scientific Meetings View Video

TCT 2023

Dr. Bon-Kwon Koo and Dr. C. Michael Gibson Discuss: EMERALD 2 View Video

Dr. Kristian Madsen and Dr. C. Michael Gibson Discuss: 3-year ADVANCE DK outcomes View Video

Dr. Josep Rodés-Cabau and Dr. C. Michael Gibson Discuss: Trancatheter Versus Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis and Small Aortic Annuli: A Randomized Clinical Trial (the VIVA Trial) View Video

Dr. Susheel K. Kodali and Dr. C. Michael Gibson Discuss: TRISCEND II: A Randomized Trial of Transcatheter Tricuspid Valve Replacement in Patients with Severe Tricuspid Regurgitation View Video

Dr. Matthias Götberg and Dr. C. Michael Gibson Discuss: Long-term Clinical Outcomes After iFR vs. FFR Guided Coronary Revascularization – Insights From the SWEDEHEART National Registry View Video | Download Slides

Dr. Myeong-Ki Hong Presents: Less Than 1-Month Dual Antiplatelet Therapy Followed by Ticagrelor Monotherapy After Coronary Drug-Eluting Stent Implantation for Acute Coronary Syndrome: A Randomized Trial | Download Slides

Dr. Robert W. Yeh and Dr. C. Michael Gibson Discuss: Primary Outcomes of a Pivotal Multicenter Randomized Trial Comparing the AGENT Paclitaxel-Coated Balloon With Conventional Balloon Angioplasty for In-Stent Restenosis View Video | Download Slides

Dr. Roberto Galea and Dr. C. Michael Gibson Discuss: One-Year Outcomes after Amulet or Watchman/FLX Device for Percutaneous Left Atrial Appendage Closure: a Pre-Specified Analysis of the SWISS-APERO Randomized Clinical Trial View Video | Download Slides

Dr. Michael J. Reardon and Dr. C. Michael Gibson Discuss: Four-Year Outcomes From the EVOLUT Low Risk Trial View Video | Download Slides

This Week in Cardiology

Dr. Michael Mack and Dr. C. Michael Gibson Discuss: Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years View Video

Dr. Timothy Fairbairn and Dr. C. Michael Gibson Discuss: The FISH&CHIPS Study View Video

This Week in Medicine®

Dr. Dean Kereiakes and Dr. C. Michael Gibson Discuss: Findings of the DISRUPT CAD III Trial 2-Year Follow-up View Video | Listen to Podcast

Dr. Kausik Ray and Dr. C. Michael Gibson Discuss: Review of the Year in Prevention and Lipids View Video | Listen to Podcast

Dr. Martha Gulati and Dr. C. Michael Gibson Discuss: Women are under-enrolled in clinical trials. Dr. Gulati and I discuss how to increase participation of women in clinical trials. View Video | Listen to Podcast

ESC 2023

Pr. Arnoud van ‘t Hof and Dr. C. Michael Gibson Discuss: What’s in the pipeline for Zalunfiban View video

Dr. Sem Rikken and Dr. C. Michael Gibson Discuss: In vitro comparison of platelet aggregation between zalunfiban and selatogrel in healthy donors View video

Dr. Shaoping Nie, Pr. Gilles Montalescot, and Dr. C. Michael Gibson Discuss: RIGHT: Prolongation of anticoagulation after Primary PCI View video | Download Slides

Dr. Jozine Ter Maaten and Dr. C. Michael Gibson Discuss: PUSH-AHF: Natriuresis guided therapy in acute heart failure View video | Download Slides

Dr. Zachary Cox and Dr. C. Michael Gibson Discuss: DICTATE-AHF: Early Dapagliflozin Initiation in Acute Heart Failure View video | Download Slides

Dr. Stephen Nicholls and Dr. C. Michael Gibson Discuss: Muvalaplin, a Potent Small Molecule Inhibitor of Lipoprotein(a) View video

Dr. Dan Jones and Dr. C. Michael Gibson Discuss: NITRATE-CIN – Inorganic nitrate to prevent CIN after angiography for ACS View video | Download Slides

Dr. Mathieu Kerneis and Dr. C. Michael Gibson Discuss: ARAMIS – Anakinra versus Placebo in Acute Myocarditis View video

Dr. Linda Joosten Presents: The FRAIL-AF randomized controlled trial Download Slides

Dr. Vivek Reddy and Dr. C. Michael Gibson Discuss: ADVENT: Pulsed Field Ablation vs Thermal Ablation (RF/Cryo) for Paroxysmal AF View video | Download Slides

Dr. Tiffany Patterson and Dr. C. Michael Gibson Discuss: ARREST trial: Expedited transfer to a cardiac arrest center for OHCA View video | Download Slides

Dr. Julian Gillmore and Dr. C. Michael Gibson Discuss: ATTRibute-CM: acoramidis (AG10) in patients with transthyretin amyloid cardiomyopathy View video

Dr. Gregg Stone and Dr. C. Michael Gibson Discuss: OCT vs. IVUS vs. angiography guidance: a real-time updated network meta-analysis View video | Download Slides

Dr. Duk-Woo Park and Dr. C. Michael Gibson Discuss: OCTIVUS: OCT- vs. IVUS-Guided PCI View video | Download Slides

Dr. Ziad Ali and Dr. C. Michael Gibson Discuss: ILUMIEN IV: OCT Versus Angiography View video | Download Slides

Dr. Masahiro Natsuaki and Dr. C. Michael Gibson Discuss: STOPDAPT-3: An Aspirin-Free antithrombotic strategy for percutaneous coronary intervention View video

Dr. Kausik Ray and Dr. C. Michael Gibson Discuss: CLEAR – Outcomes analysis by glycaemic status View video

Dr. Holger Thiele and Dr. C. Michael Gibson Discuss: ECLS-SHOCK – venoarterial membrane oxygenation in cardiogenic shock View video | Download Slides

Dr. Stephen Nicholls and Dr. C. Michael Gibson Discuss: CLEAR – Outcomes total events analysis View video

Dr. Simone Biscaglia and Dr. C. Michael Gibson Discuss: FIRE trial: Physiology-Guided Complete PCI in Older MI Patients View video | Download Slides

Dr. Robert Mentz and Dr. C. Michael Gibson Discuss: HEART-FID: Ferric Carboxymaltose in Heart Failure with Iron Deficiency View video | Download Slides

Pr. Bela Merkely and Dr. C. Michael Gibson Discuss: BUDAPEST CRT Upgrade: Cardiac resynchronisation therapy upgrade in heart failure with right ventricular pacing – a multicentre, randomised, controlled trial View video | Download Slides

Dr. David Conen and Dr. C. Michael Gibson Discuss: COP-AF – Colchicine for the prevention of perioperative atrial fibrillation after major thoracic surgery View video

Reducing High-risk PE Mortality: A FLAME Town Hall

Dr. Thomas Tu, Dr. Mitchell Silver, Dr. Jay Giri, Dr. Wissam Jaber, and Dr. C. Michael Gibson Discuss: Reducing High-risk PE Mortality: A FLAME Town Hall – June 21, 2023 View content on microsite here

Snackable Health

Dr. Dominick Angiolillo and Dr. C. Michael Gibson Discuss: A common question in clinical practice which is “How do I switch a patient from Ticagrelor to Clopidogrel?” View Video

Dr. Dominick Angiolillo and Dr. C. Michael Gibson Discuss: Academic Research Consortium (ARC) definitions surrounding reductions in dose, switches between agents and discontinuation of thienopyridines View Video | Download Slides

Snackable Health with Dr. C. Michael Gibson and Dr. Payal Kohli View content on microsite here

ADA 2023

Dr. Steven Nissen and Dr. C. Michael Gibson Discuss: Outcomes for Primary Prevention Patients in the CLEAR Outcomes Trial View Video | Download Slides

ESC-HFA 2023

Dr. Javed Butler, Dr. Jim Januzzi, Dr. Harriette Van Spall and Dr. C. Michael Gibson Discuss: ESC Heart Failure Association Wrap-up – May 23, 2023 View Video

Dr. James Januzzi and Dr. C. Michael Gibson Discuss: TRACER-HF: Trientine-HCL for treatment of heart failure and reduced ejection fraction View Video

ACCess POINTS – ACC 2023

Dr. Suzanne Baron, Dr. Deepak Bhatt and Dr. C. Michael Gibson Discuss: ACC 2023 ACCess Points Daily Wrap-up – March 5, 2023 View Video

Dr. Javed Bulter, Dr. Rasha Al-Lamee and Dr. C. Michael Gibson Discuss: ACC 2023 ACCess Points Daily Wrap-Up – March 4, 2023 View Video

Dr. Paul Ridker and Dr. C. Michael Gibson Discuss: Residual Inflammatory Risk In Contemporary Statin Treated Patients: A Collaborative Analyses Of 31,197 Participants In The Prominent, Reduce-it, And Strength Trials View Video

Katherine Martinez, Dr. Michael Ackerman, Dr. Matthew Martinez and Dr. C. Michael Gibson Discuss: Return-to-play For Elite Level Athletes With Sudden Cardiac Death Predisposing Genetic Heart Diseases View Video

Dr. Rachel Lampert, Dr. Sharlene Day and Dr. C. Michael Gibson Discuss: Vigorous Exercise In Individuals With Hypertrophic Cardiomyopathy (HCM): Primary Results Of The Prospective, Multinational Lifestyle And Exercise In HCM (LIVE-HCM) Study View Video

Dr. Christie Ballantyne and Dr. C. Michael Gibson Discuss: Efficacy And Safety Of The Oral PCSK9 Inhibitor, MK-0616, A Macrocyclic Peptide, In The Treatment Of Hypercholesterolemia: A Phase 2b Randomized Placebo-Controlled Clinical Trial View Video

Dr. Braden Manns and Dr. Pratik Doshi Discuss: A Randomized Trial Assessing The Impact Of Eliminating Copayment For High Value Preventive Medications For Low-income Seniors With Cardiovascular-related Chronic Diseases View Video

Dr. Raj Makkar and Dr. C. Michael Gibson Discuss: Safety And Efficacy Of Transcatheter Edge-to-Edge Mitral Repair In Degenerative Mitral Regurgitation: An Analysis Of The STS/ACC TVT Registry View Video

Dr. John Forrest and Dr. C. Michael Gibson Discuss: Transcatheter Versus Surgical Aortic Valve Replacement In Aortic Stenosis Patients At Low Surgical Risk: 3-year Outcomes From The Evolut Low Risk Trial View Video

Dr. Steven Nissen and Dr. C. Michael Gibson Discuss: Bempedoic Acid And Cardiovascular Outcomes In Statin Intolerant Patients At High Cardiovascular Risk View Video | Download Slides

ACC 2023

Dr. Ginger Jiang, Dr. Serge Korjian, and Dr. Yazan Daaboul Discuss: ACC 2023 Fellows Wrap-up View Video

Dr. Xavier Escudero and Dr. Jose Luis Levia Pons Discuss: ACC 2023 Wrap-up in Spanish View Video

Dr. Ankeet Bhatt and Dr. C. Michael Gibson Discuss: Safety and Efficacy of Virtual Care Team Guided Therapeutic Optimization During Hospitalization in Patients With HFrEF: The IMPLEMENT-HF Study View Video

Dr. Barry Borlaug and Dr. C. Michael Gibson Discuss: CAMEO-DAPA Trial: Evaluation of the Mechanism of Benefit For Dapagliflozin in Heart Failure With Preserved Ejection Fraction: An Invasive Hemodynamic Randomized Trial View Video | Download Slides

Dr. Myeong-Ki Hong and Dr. C. Michael Gibson Discuss: The LOADSTAR Trial: Comparison Between Targeted Low-Density Lipoprotein Cholesterol Level Based Versus High-Intensity Statin Therapy in Patients With Coronary Artery Disease View Video

Dr. Gregg Stone and Dr. C. Michael Gibson Discuss: Anticoagulation Strategies in Non-critically Ill Hospitalized Covid-19 Patients: Principal Outcomes of the Freedom Covid Anticoagulation Trial View Video

Dr. Neha Pagidipati and Dr. C. Michael Gibson Discuss: Coordinating Cardiology Clinics Randomized Trial of Interventions to Improve Outcomes (COORDINATE)-Diabetes: Primary Results View Video

Dr. Atul Verma and Dr. C. Michael Gibson Discuss: PULSED Field Ablation Treatment in Paroxysmal and Persistent Atrial Fibrillation Patients: Acute and Long-term Outcomes From the PULSED AF Pivotal Trial View Video

Dr. Mitchell Silver, Dr. Jay Giri, and Dr. C. Michael Gibson Discuss: Outcomes in High-risk Pulmonary Embolism Patients Undergoing FlowTriever Mechanical Thrombectomy: Results From The FLAME Study View Video

Dr. Dirk Westermann and Dr. Yazan Daaboul Discuss: Prediction of Preeclampsia Using High-Sensitivity Troponin I View Video

Dr. Hyo-Soo Kim and Dr. C. Michael Gibson Discuss: Comparison of 3-month Versus 12-month Dual Antiplatelet Therapy After Coronary Intervention Using the Contemporary Drug-eluting Stents With Ultrathin Struts And Advanced Polymer Technology: The HOST-IDEA Randomized Clinical Trial View Video | Download Slides

Dr. Iulia Iatan and Dr. C. Michael Gibson Discuss: Association of a Low-carbohydrate High-fat (Ketogenic) Diet With Plasma Lipid Levels and Cardiovascular Risk in a Population-based Cohort View Video

Dr. Barry Borlaug and Dr. C. Michael Gibson Discuss: RAPID-HF: Atrial Pacing For Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial View Video

Dr. Roberto Diletti and Dr. C. Michael Gibson Discuss: BIOVASC: Complete Revascularization Strategies in Patients Presenting With Acute Coronary Syndromes and Multivessel Coronary Disease View Video

Dr. Gregg Stone and Dr. C. Michael Gibson Discuss: Transcatheter Edge-to-edge Repair of Functional Mitral Regurgitation in Heart Failure: Final Five-year Results From the COAPT Trial View Video | Download Slides

Dr. Joo-Yong Hahn and Dr. C. Michael Gibson Discuss: RENOVATE-COMPLEX-PCI: Intravascular Imaging-guided Versus Angiography-guided Procedural Optimization in Complex Percutaneous Coronary Intervention View Video

Dr. Enoch Akowuah and Dr. C. Michael Gibson Discuss: Minimally Invasive Versus Conventional Sternotomy For Mitral Valve Repair Surgery: An Expertise Based Multicentre Randomised Controlled Trial (UK Mini Mitral) View Video | Download Slides

Dr. Annapoorna Subhash Kini and Dr. C. Michael Gibson Discuss: Effect of Evolocumab on Coronary Plaque Characteristics in Stable Coronary Artery Disease: A Multimodality Imaging Study (the Yellow III Study) View Video

Dr. Divaka Perera and Dr. C. Michael Gibson Discuss: Effect of Myocardial Viability, Percutaneous Coronary Intervention and Functional Recovery on Clinical Outcomes in the REVIVED-BCIS2 Randomized Trial View Video | Download Slides

Dr. Tomas Neilan, Dr. Marielle Scherrer-Crosbie, and Dr. C. Michael Gibson Discuss: Statins TO Prevent the Cardiotoxicity From Anthracyclines: The STOP-CA Trial View Video

Heart Success

Dr. Carolyn Lam and Dr. C. Michael Gibson Discuss: Heart Failure Trials at AHA 2022 View Video

Dr. Carolyn Lam and Dr. C. Michael Gibson Discuss: Updates to the ESC CHF Guidelines and How to Initiate Medications to Optimize Outcomes View Video

Dr. Carolyn Lam Presents: The Results of the EMPEROR PRESERVED Trial Video Video

Dr. Carolyn Lam and Dr. C. Michael Gibson Discuss How to Initiate Heart Failure Drug View Video

Dr. Carolyn Lam and Dr. C. Michael Gibson Talk About Success in the Battle Against Heart Failure View Video

Aspirin Therapy in 2022: New Horizons

A CME-Jointly Accredited Program View content on microsite here

Design Education

Design as API Between Technology and Humanity: Speech given at the Massachusetts Institute of Technology by Gerald Chan Download Speech

ACCess POINTS – AHA 2022

Dr. Rasha Al-Lamee and Dr. C. Michael Gibson Discuss: AHA 2022 ACCess Points Daily Wrap-Up – November 7, 2022 View Video

Dr. Payal Kohli and Dr. C. Michael Gibson Discuss: AHA 2022 ACCess Points Daily Wrap-Up – November 6, 2022 View Video

Dr. Julia Grapsa and Dr. C. Michael Gibson Discuss: AHA 2022 ACCess Points Daily Wrap-Up – November 5, 2022 View Video

Dr. Marc Bonaca and Dr. C. Michael Gibson Discuss: Aortic Disease Guidelines View Video

Dr. Cian McCarthy and Dr. C. Michael Gibson Discuss: Implementation of High-Sensitivity Cardiac Troponin Assays in the United States View Video

Dr. Steve Nissen, Dr. Luke Laffin, and Dr. C. Michael Gibson Discuss: Comparative Effects of Low-Dose Rosuvastatin, Placebo and Dietary Supplements on Lipids and Inflammatory Biomarkers View Video

AHA 2022

Dr. Ceclia Bahit and Dr. C. Michael Gibson Discuss: AHA 2022 Daily Wrap up in Spanish View Video

Dr. Payal Kohli and Dr. C. Michael Gibson Discuss: Deep Dive on Prevention Trials at AHA 2022 View Video

Dr. David Kandzari and Dr. C. Michael Gibson Discuss: SPYRAL HTN-ON – Effect of Radiofrequency Renal Denervation on Blood Pressure in the Presence of Antihypertensive Drugs: 6-Month Primary Results from the SPYRAL HTN-ON Med Expansion Randomized Trial View Video | Download Slides

Dr. Jonathan Piccini and Dr. C. Michael Gibson Discuss: NOVA – Efficacy and Safety of Botulinum Toxin Type A for the Prevention of Postoperative Atrial Fibrillation in Cardiac Surgery Patients: Results from the Phase 2 Nova Study View Video | Download Slides

Dr. Matthew Budoff and Dr. C. Michael Gibson Discuss: STOP – Effect of Semaglutide on Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes: Final Results of the Stop Study View Video | Download Slides

Dr. Hyo Soo Kim and Dr. C. Michael Gibson Discuss: HOST-EXAM – Long Term Follow-Up of Aspirin vs. Clopidogrel Monotherapy in the Chronic Maintenance Period After Percutaneous Coronary Intervention: The Host-Exam Extended Study View Video | Download Slides

Dr. Erlend Berg and Dr. C. Michael Gibson Discuss: After Eighty Study – Long-Term Outcomes of an Invasive versus Conservative Strategy in Stabilised Patients Aged 80 Years or Older With Non-ST-Elevation Acute Coronary Syndrome, After Eighty Study: A Randomised Controlled Trial View Video | Download Slides

Dr. Judith Hochman and Dr. C. Michael Gibson Discuss: ISCHEMIA-EXTENDed – Follow-Up Interim Report View Video | Download Slides

Dr. Pamela Douglas and Dr. C. Michael Gibson Discuss: PRECISE – Comparison of a Precision Care Strategy with Usual Testing to Guide Management of Stable Patients With Suspected Coronary Artery Disease: The Precise Randomized Trial View Video | Download Slides

Dr. Michelle O’Donoghue and Dr. C. Michael Gibson Discuss: OCEAN(a)-DOSE – Reduction of Lipoprotein(a) With Small Interfering RNA: The Results of the Ocean(a)-DOSE Trial View Video | Download Slides

Dr. Hiroyuki Daida and Dr. C. Michael Gibson Discuss: RESPECT-EPA – Randomized Trial for Evaluating Secondary Prevention Efficacy of Combination Therapy – Statin and Eicosapentaenoic Acid View Video

Dr. Gregg Stone and Dr. C. Michael Gibson Discuss: BRIGHT-4 – Bivalirudin With a Post-PCI High-Dose Infusion versus Heparin Monotherapy During Primary PCI in STEMI: The Randomized Bright-4 Trial View Video | Download Slides

Dr. Mark Huffman and Dr. Yazan Daaboul Discuss: QUARTET USA – Efficacy and Safety of a Quadruple Ultra-Low-Dose Treatment for Hypertension (QUARTET USA): A Randomized Controlled Trial View Video | Download Slides

Dr. Dominick Angiolillo Presents: From Dual Antiplatelet Treatment Regimens With Aspirin Plus a P2Y12 Inhibitor to Dual Pathway Inhibition With Low-Dose Rivaroxaban in Adjunct to Aspirin in Patients With Coronary Artery Disease: The SWAP-AC Study Download Slides

Dr. Dominick Angiolillo Presents: Pharmacodynamic and Pharmacokinetic Profiles of Switching Between Cangrelor and Ticagrelor Following Ticagrelor Pre-Treatment: The SWAP-5 Study Download Slides

Dr. Petr Ostadal and Dr. C. Michael Gibson Discuss: ECMO-CS – Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock: Primary Results from the Multicenter, Randomized ECMO-CS Trial View Video | Download Slides

Dr. James Jollis, Dr. Jacqueline Tamis-Holland, and Dr. C. Michael Gibson Discuss: Treatment Time and In-Hospital Mortality Among Patients With ST-Segment Elevation Myocardial Infarction, 2018-2021 View Video | Download Slides | Download Manuscript

Dr. David Hare and Dr. Yazan Daaboul Discuss: RAPCO – Radial Artery Patency and Clinical Outcomes (RAPCO) Randomized Trials – The 15-Year Clinical Outcomes Comparing Radial Artery with Right Internal Thoracic Artery or With Saphenous Vein Grafting View Video | Download Slides

Dr. Paul Kalra and Dr. C. Michael Gibson Discuss: IRONMAN – Randomized Trial of Intravenous Ferric Derisomaltose in Heart Failure with Reduced Ejection Fraction View VideoDownload Slides

Dr. Julian Gillmore, Dr. David Lebwohl, and Dr. C. Michael Gibson Discuss: First-in-Human in vivo Crispr/Cas9 Editing of the Ttr Gene by Ntla-2001 in Patients with Transthyretin Amyloidosis With Cardiomyopathy View Video | Download Slides

Dr. Aruna Pradhan Presents: PROMINENT – A Randomized Trial of Pemafibrate for Triglyceride Reduction in the Prevention of Cardiovascular Disease Download Slides

Dr. Areef Ishani and Dr. Yazan Daaboul Discuss: DCP – Chlorthalidone Compared to Hydrochlorothiazide for the Prevention of Cardiovascular Events in Patients with Hypertension View Video

Dr. Robert Mentz and Dr. C. Michael Gibson Discuss: TRANSFORM-HF – Comparative Effectiveness of Torsemide versus Forsumid in Heart Failure: Primary Results of the TRANSFORM-HF Trial View Video | Download Slides

Aspirin

Dr. Bryon Cryer and Dr. C. Michael Gibson Discuss: Gastrointestinal Toxicity of Aspirin: the Pathophysiology of the Problem and the Pathophysiologically Guided Solution View Video

Dr. C. Michael Gibson Presents: Secondary Prevention with Aspirin – Learn about the Latest FDA Approved Aspirin Formulation View Video | Download Slides

Dr. Neha J. Pagidipati, Dr. Jacqueline E. Tamis-Holland, Dr. Dominick J. Angiolillo and Dr. C. Michael Gibson Discuss: Aspirin in 2022: A New Aspirin for a New Chapter – Clarifying Aspirin Therapy in Secondary Prevention and DAPT for the Practicing Clinician: A Town Hall View Video | Download Slides

Dr. Michelle L. O’Donoghue, Dr. Ann Marie Navar, Dr. Martha Gulati, Dr. Christoper Cannon, Dr. Dominick J. Angiolillo, and Dr. C. Michael Gibson Discuss: Should You Stop (or Start) Aspirin? Ask Your Doctor – Clarifying the Continued Role of Aspirin in Secondary Prevention: A Town Hall View Video | Download Slides

Atrial Fibrillation

Dr. Walid Saliba and Dr. C. Michael Gibson Discuss: The Next Generation of WATCHMAN FLX – Video #2 View Video

Dr. Walid Saliba and Dr. C. Michael Gibson Discuss: The Next Generation of WATCHMAN FLX – Video #1 View Video

CDC

Dr. Jonathan Reiner and Dr. C. Michael Gibson Discuss: What the Best Path Forward for the CDC Might Look Like View Video

LDL-lowering Therapies

Dr. Kausik Ray and Dr. C. Michael Gibson Discuss: The Verve Therapeutics Gene Editing Approach to Lowering LDL in Familial Hypercholesterolemia View Video

Dr. Kausik Ray and Dr. C. Michael Gibson Discuss: Reimagining Prevention from a Public Healthcare Perspective View Video

Dr. Kausik Ray and Dr. C. Michael Gibson Discuss: Non-LDL Lipid Lowering Targets for Event Reduction View Video

WIN Ratio

Dr. Andrew Althouse and Dr. C. Michael Gibson Discuss: Demystifying the Win Ratio View Video

Search archived content (2018 and prior)