Clinical Trial Results Archive (2020)


Coronary Artery Disease

Dr. Dean Kereiakes and Dr. C. Michael Gibson Discuss Shockwave FDA Approval Video

Heart Success

Dr. Carolyn Lam and Dr. C. Michael Gibson Discuss How to Initiate Heart Failure Drugs Video

Dr. Carolyn Lam and Dr. C. Michael Gibson Talk About Success in the Battle Against Heart Failure Video

AHA 2020

Dr. Robert Harrington and Dr. C. Michael Gibson Discuss: The AHA COVID-19 Cardiovascular Disease Registry: Design, Implementation, and Initial Results Video
Dr. John Teerlink and Dr. C. Michael Gibson Discuss: Omecamtiv Mecarbil in Chronic Heart Failure With Reduced Ejection Fraction: The Global Approach to Lowering Adverse Cardiac Outcomes Through Improving Contractility in Heart Failure (GALACTIC-HF) Trial Video
Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: AHA 2020 Daily Wrap-Up - November 16, 2020 Video
Dr. Pierre Amarenco Dr. Pierre Amarenco Presents: Ticagrelor Added to Aspirin in Acute Ischemic Stroke or Tia of Atherosclerotic Origin Slides
Dr. Deepak Bhatt Dr. Deepak Bhatt and C. Michael Gibson Discuss: Divergent Results in the STRENGTH and REDUCE-IT trials Video
Dr. Deepak Bhatt and C. Michael Gibson Discuss: The SOLOIST-WHF and SCORED Trials: Sotagliflozin in Diabetes Patients Video
Dr. Steven Steinhubl Dr. Steven Steinhubl and Dr. C. Michael Gibson Discuss: 3-year Clinical Outcomes In A Nationwide, Randomized, Pragmatic Clinical Trial Of Atrial Fibrillation Screening - Mhealth Screening To Prevent Strokes (mstops) Video
Dr. Alexandra J Lansky Dr. Alexandra J Lansky Presents: A Prospective Multicenter Randomized Controlled Trial Assessing the Safety and Efficacy of the BuMA Supreme™ Biodegradable Drug Coated Coronary Stent System in Patients With Stable or Non-ST Elevation Acute Coronary Syndromes: Primary Endpoint Results of the PIONEER III Trial Slides
Dr. A. Michael Lincoff Dr. A. Michael Lincoff and Dr. C. Michael Gibson Discuss: STRENGTH Trial: Cardiovascular Outcomes With Omega-3 Carboxylic Acids (Epanova) In Patients With High Vascular Risk And Atherogenic Dyslipidemia Video
Dr. Otavio Berwanger Dr. Otavio Berwanger and Dr. C. Michael Gibson Discuss: Rivaroxaban Versus Warfarin In Patients With Bioprosthetic Mitral Valves And Atrial Fibrillation Or Flutter: Primary Results From The RIVER Randomized Trial Video | Slides
Dr. Renato Lopes Dr. Renato Lopes and Dr. C. Michael Gibson Discuss: Rivaroxaban Versus Warfarin In Patients With Bioprosthetic Mitral Valves And Atrial Fibrillation Or Flutter: Primary Results From The RIVER Randomized Trial Video
Dr. Johanne Silvain Dr. Johanne Silvain Presents: Ticagrelor versus Clopidogrel in Elective Percutaneous Coronary Intervention : The Alpheus Trial Slides
Dr. Salim Yusuf Dr. Salim Yusuf and Dr. C. Michael Gibson Discuss: Aspirin Alone And In Combination With A Polypill In Cardiovascular Disease Primary Prevention: Results From The International Polycap Study (TIPS)-3 Video
Dr. Prem Pais Dr. Prem Pais and Dr. Serge Korjian Discuss: A Polypill For Primary Prevention Of Cardiovascular Disease In Intermediate Risk People: Results Of The International Polycap Study (TIPS)-3 Video

TCT 2020

Dr. Catalin Toma Dr. Catalin Toma and Dr. C. Michael Gibson Discuss: FLASH Registry: Acute Hemodynamic Improvement With Percutaneous Mechanical Thrombectomy in a Real-world Pulmonary Embolism Population Video | Slides
Dr. Ehrin Armstrong Dr. Ehrin Armstrong and Dr. C. Michael Gibson Discuss: TANGO: A Randomized Dose-Escalation Trial of Temsirolimus Adventitial Delivery to Improve Below the Knee Outcomes Video | Slides
Dr. Andrew Holden Dr. Andrew Holden and Dr. C. Michel Gibson: ILLUMENATE: Four-Year Results With a Low-Dose Paclitaxel Drug-Coated Balloon in De Novo And Restenotic Femoropopliteal Lesions Video | Slides
Dr. Ajay Kirtane Dr. Roxana Mehran Dr. Mamas Mamas Dr. Ajay Kirtane, Dr. Roxana Mehran, Dr. Mamas Mamas and Dr. C. Michael Gibson Discuss: TCT 2020 Daily Wrap-Up - October 16, 2020 Video
Dr. Ajay Kirtane, Dr. Roxana Mehran, Dr. Mamas Mamas and Dr. C. Michael Gibson Discuss: TCT 2020 Daily Wrap-Up - October 17, 2020 Video
Dr. Dean Kereiakes Dr. Dean Kereiakes and Dr. C. MIchael Gibson Discuss: OPTIMIZE: A Randomized Trial of a Novel, Ultra Low Profile Fixed-Wire DES Video | Slides
Dr. Dean Kereiakes and Dr. C. Michael Gibson Discuss: Disrupt CAD III: Safety and Effectiveness of Intravascular Lithotripsy for Treatment of Severe Coronary Calcification Video | Slides
Dr. Robert Byrne Dr. Robert Byrne and Dr. C. Michael Gibson Discuss: COBRA-REDUCE: A Randomized Trial of a Thromboresistant Polyzene F-Coated Stent With 14 Days DAPT in High-Bleeding Risk Patients Video | Slides
Dr. Hyo-Soo Kim Dr. Hyo-Soo Kim Presents: Host-Reduce-Polytech-ACS: A Randomized Trial of Durable Polymer vs Bioabsorbable Polymer DES in Patients With Acute Coronary Syndromes Slides
Dr. Nils Johnson Dr. Nils Johnson Presents: The DEFINE-FLOW study combined CFR and FFR assessment Slides
Dr. Damien Collison Dr. Damien Collison and Dr. C. Michael Gibson Discuss: TARGET FFR: A Randomized Trial of Physiology-Guided PCI Optimization Video | Slides
Dr. Nick Curzen Dr. Nick Curzen Presents: FORECAST: A Randomized Trial of CTA/FFRCT Decision-making in Patients With Chest Pain Slides
Dr. Ajay Kirtane Dr. Ajay Kirtane and Dr. C. Michael Gibson Discuss: TCT 2020 Daily Wrap-Up - October 15, 2020 Video
Dr. Junjie Zhang Dr. Junjie Zhang and Dr. C. Michael Gibson Discuss: ULTIMATE: Three-Year Outcomes After IVUS-Guided vs Angiography Guided DES Implantation Video | Slides
Dr. Roxana Mehran Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: XIENCE 90/28: Assessment of Three-Month and One-Month DAPT After Everolimus-Eluting Stents in High-Bleeding Risk Patients Video | Slides
Dr. Timothy Henry Dr. Timothy Henry and Dr. C. Michael Gibson Discuss: NACMI: Outcomes From the North American COVID-19 STEMI Registry Video | Slides
Dr. Philipp Lurz Dr. Philipp Lurz and Dr. C. Michael Gibson Discuss: MITHRAS: A Randomized Trial of ASD Closure After TMVr Video | Slides
Dr. Jeffrey Moses Dr. Jeffrey Moses and Dr. C. Michael Gibson Discuss: REFLECT II: A Randomized Trial of a Cerebral Embolic Protection Device During TAVR Video | Slides
Dr. Corrado Tamburino Dr. Corrado Tamburino and Dr. C. Michael Gibson Discuss: SCOPE II: A Randomized Trial of Two Self-expanding TAVR Bioprostheses Video | Slides
Dr. Georgios Vlachojannis Dr. Georgios Vlachojannis and Dr. C. Michael Gibson Discuss: COMPARE CRUSH: A Randomized Trial of Prehospital Crushed vs Uncrushed Prasugrel in STEMI Video | Slides
Dr. Ajay Kirtane Dr. Roxana Mehran Dr. Ajay Kirtane, Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: TCT 2020 Daily Wrap-Up - October 14, 2020 Video
Dr. Byeong-Keuk Kim Dr. Byeong-Keuk Kim and Dr. C. Michael Gibson Discuss: TICO-STEMI: A Randomized Trial of Ticagrelor Monotherapy vs Ticagrelor With Aspirin in STEMI Video | Slides
Dr. Gregg Stone Dr. Gregg Stone and Dr. C. Michael Gibson Discuss: PROSPECT ABSORB: A Randomized Trial of Interventional Treatment of Vulnerable Plaques Video | Slides
Dr. Gregg Stone and Dr. C. Michael Gibson Discuss: Bivalirudin vs Heparin in Patients With Myocardial Infarction: An Individual Patient Data Pooled Analysis Video | Slides

COVID-19 Videos

Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: The Second Wave of COVID in New York City Video
Dr. Victor Tapson, Dr. Gregory Piazza, Dr. Alex Spyropoulos, Dr. Samuel Goldhaber and Dr. C Michael Gibson Discuss: Thrombosis in the Setting of COVID Video
Dr. Rob Califf Dr. Rob Califf and Dr. C. Michael Gibson Discuss: Clinical Trials of the Future Video
Dr. Robert Harrington Dr. Robert Harrington and Dr. C. Michael Gibson Discuss: Navigating a Pandemic as a Department of Medicine Chairman Video
Dr. Renato Lopes Dr. Renato Lopes and Dr. C. Michael Gibson Discuss: BRACE CORONA - Continuing versus Suspending Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers: Impact on Adverse Outcomes in Hospitalized Patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Video
Dr. Eric Topol Dr. Eric Topol and Dr. C. Michael Gibson Discuss: Cytokine Storm and Coronavirus Video
Dr. Eric Topol and Dr. C. Michael Gibson Discuss: Herd Immunity, Re-infection, Re-activation and Seroprevalence Video
Dr. Eric Topol and Dr. C. Michael Gibson Discuss: Digital Testing of Heart Rate and Temperature to Identify New Coronavirus Cases Video
Dr. Eric Topol and Dr. C. Michael Gibson Discuss: Lack of Testing and Protective Gear and Efforts to Organize Young Physicians to Safeguard Their Interests Video



Dr. Duk-Woo Park Dr. Duk-Woo Park and Dr. C. Michael Gibson Discuss: How South Korea was Able to Flatten the Curve in the Coronavirus Epidemic Video
Dr. Carolyn Lam Dr. C. Michael Gibson and Dr. Carolyn Lam Discuss: Flattening the Coronavirus Curve: Lessons from Singapore Video
Dr. Dominick Angiolillo Dr. C. Michael Gibson and Dr. Dominick Angiolillo Discuss: The Impact of Coronavirus on Italian Healthcare Video
Dr. Ajay Kirtane Dr. C. Michael Gibson and Dr. Ajay Kirtane Discuss: Coronavirus Update – March 26, 2020 Video
Dr. George Dangas Dr. George Dangas and Dr. C. Michael Gibson Discuss: Live Update on the COVID-19 Outbreak from New York Video
Dr. C. Michael Gibson and Jani Tuomi Dr. C. Michael Gibson and Jani Tuomi Discuss: Using Telemedicine to Connect Patients with COVID-19 Testing Video

ST-Elevation Myocardial Infarction

Dr. Dean Kereiakes Dr. Dean Kereiakes and Dr. C. Michael Gibson Discuss: RUC-4, a novel small molecule Platelet GPIIb/IIIa inhibitor designed for subcutaneous point of first contact STEMI treatment Video

ESC 2020

Pr. Dr. Sigmund Silber Pr. Dr. Sigmund Silber Presents: ESC 2020 Wrap-Up in German Video
Dr. Roxana Mehran Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: Changes to the NSTEMI guidelines and Popular TAVI Video
Dr. Roxana Mehran and Dr. C. Michael Gibson Discuss: Open Access at ESC 2020 Video
Caroyln Lam Dr. Carolyn Lam and Dr. C. Michael Gibson Discuss: ESC 2020 With a Focus This Year on Advances in Heart Failure and Renal Failure Video
Dr. Renato Lopes Dr. Renato Lopes and Dr. C. Michael Gibson Discuss: BRACE CORONA: Continuing vs. Suspending ACE Inhibitors and ARBs in COVID-19 Video | Slides
Dr. Burkert Pieske Dr. Burkert Pieske and Dr. C. Michael Gibson Discuss: PARALLAX: Sacubitril/Valsartan versus Individualized RAAS Blockade in Patients with HFpEF Video
Sean Pokorney Dr. Sean Pokorney Presents: IMPACT-Afib Implementation of Stroke Prevention in Atrial Fibrillation Slides
Dr. Paulus Kirchhof Dr. Paulus Kirchhof and Dr. C. Michael Gibson Discuss: EAST – AFNET 4: Effects of Early Rhythm Control Therapy in Patients with Atrial Fibrillation Video | Slides
Dr. Kazem Rahimi Dr. Kazem Rahimi and Dr. C. Michael Gibson Discuss: BPLTTC - Blood Pressure Lowering for Prevention of Cardiovascular Events across Different Levels of Blood Pressure Video
Dr. Jan Cornel Dr. Jan Cornel and Dr. C. Michael Gibson Discuss: LoDoCo2 Low-Dose Colchicine in Coronary Disease Video | Slides
Dr. Pierre-Marie Roy Dr. Pierre-Marie Roy and Dr. C. Michael Gibson Discuss: HOME-PE - Hospitalisation or Outpatient Management of PE Patients - HESTIA vs. Simplified PESI Video
Dr. Jorn Brouwer Dr. Jorn Brouwer and Dr. C. Michael Gibson Discuss: POPULAR TAVI - Aspirin With or Without Clopidogrel after Transcatheter Aortic Valve Implantation Video | Slides
Dr. Iacopo Olivotto Dr. Iacopo Olivotto and Dr. C. Michael Gibson Discuss: EXPLORER-HCM: Efficacy and Safety of Mavacamten in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy Video | Slides
Dr. Milton Packer Dr. Milton Packer and Dr. C. Michael Gibson Discuss: EMPEROR-Reduced: Empagliflozin in Heart Failure With a Reduced Ejection Fraction, With and Without Diabetes Video | Slides

Percutaneous Coronary Intervention

Dr. Dominick Angiolillo Dr. Dominick Angiolillo Presents: Safety and Efficacy of Double Antithrombotic Therapy with Non–vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis Slides
Dr. Marco Valgimigli Dr. Marco Valgimigli and Dr. C. Michael Gibson Discuss: Facilitation Through Aggrastat or Cangrelor Bolus and Infusion Over PrasugreL: a MUlticenter Randomized Open-label Trial in PatientS with ST-elevation Myocardial InFarction Referred for PrimAry PercutaneouS InTERvention (FABOLUS FASTER) Trial: Design and Rationale Video

Preprint Servers

Dr. Harlan Krumholz Dr. Harlan Krumholz and Dr. C. Michael Gibson Discuss: Preprint’s Future is Now Video

P2Y12 Inhibtors

Dr. Stephan James Dr. Eliano Navarese Dr. Stephan James, Dr. Eliano Navarese and Dr. C. Michael Gibson Discuss: Comparative Efficacy and Safety of Oral P2Y12 Inhibitors in Acute Coronary Syndrome - Network Meta-Analysis of 52,816 Patients From 12 Randomized Trials Video

Spontaneous Coronary Artery Dissection

National SCAD Town Hall Panelists Dr. Malissa Wood, Kevin Fitzpatrick, Dr. Esther Kim, Dr. Sahar Naderi, Katherine Leon, Nancy McCleary, Dr. Brian Ghosshhajra, Dr. Jennifer Sumner, Dr. Uri Elkayam, Dr. Mark Lindsay, Dr. Kathy Economy, Dr. Tina Pittman Wagers and Dr. C. Michael Gibson Discuss: National SCAD Town Hall - Your Questions Answered Video

Digital Identity

Dr. Leah Houston Dr. Leah Houston and Dr. C. Michael Gibson Discuss: How Do We Restore Privacy to the Practice of Medicine? Video

ACC 2020

Dr. Pamela S. Douglas Dr. Pamela S. Douglas and Dr. C. Michael Gibson Discuss: Dr. Pamela Douglas: Her Life in Her Words Video
Dr. Vincent Nijenhuis Dr. Vincent Nijenhuis and Dr. C. Michael Gibson Discuss: Antithrombotic Therapy After Transcatheter Aortic Valve Implantation In Patients With A Long-term Indication For Oral Anticoagulation (POPular TAVI Trial - Cohort B) Video | Slides
Dr. Piotr Ponikowski Dr. Piotr Ponikowski and Dr. C. Michael Gibson Discuss: Benefit Of Dapagliflozin On First And Repeat Events In Patients With HFrEF In DAPA-HF Video
Dr. Pamela S. Douglas Dr. Pamela S. Douglas and Dr. C. Michael Gibson Discuss: ACC Names Diversity and Inclusion Award After Dr. Pamela S. Douglas: She Talks Past, Present, and Future Challenges Here Video
Dr. Dirk Blom Dr. Dirk Blom and Dr. C. Michael Gibson Discuss: Alirocumab Efficacy And Safety In Adults With Homozygous Familial Hypercholesterolemia (ODYSSEY HoFH) Video
Dr. Sripal Bangalore Dr. Sripal Bangalore and Dr. C. Michael Gibson Discuss: Clinical And Quality Of Life Outcomes With Invasive Versus Conservative Strategy In Patients With Stable Ischemic Heart Disease Across The Spectrum Of Baseline Kidney Function: Insights From The ISCHEMIA And ISCHEMIA-CKD Trials Video | Slides
Dr. Laxmi S. Mehta Dr. Laxmi S. Mehta Dr. C. Michael Gibson Discuss: Practice Factors Affecting Cardiologists’ Wellbeing: The American College Of Cardiology 2019 Well Being Study Video | Slides
Dr. Marc Bonaca Dr. Marc Bonaca and Dr. C. Michael Gibson Discuss: Rivaroxaban For Prevention Of Cardiovascular And Limb Events After Lower Extremity Revascularization: Primary Results Of The Voyager Pad Randomized Trial Video | Slides
Dr. Harmony Reynolds Dr. Harmony Reynolds Presents: Natural History Of Symptoms And Stress Echo Findings In Patients With Moderate Or Severe Ischemia And No Obstructive CAD (INOCA): The NHLBI-funded CIAO Ancillary Study To The ISCHEMIA Trial Slides
Dr. Deepak Bhatt Dr. Deepak Bhatt and Dr. C. Michael Gibson Discuss: Eicosapentaenoic Acid Levels in REDUCE-IT and Cardiovascular Outcomes Video | Slides
Dr. Mark J. Eisenberg Dr. Mark J. Eisenberg and Dr. C Michael Gibson Discuss: A Randomized Controlled Trial Evaluating The Efficacy And Safety Of E-Cigarettes For Smoking Cessation Video | Slides
Dr. D. Scott Lim Dr. D. Scott Lim and Dr. C. Michael Gibson Discuss: Contemporary Outcomes With Mitraclip™ (NTR/XTR) System In Primary Mitral Regurgitation: Results From The Global Expand Study Video | Slides
Dr. Dominick Angiolillo Dr. Dominick Angiolillo and Dr. C. Michael Gibson Discuss: Ticagrelor With And Without Aspirin In High-Risk Patients With Diabetes Mellitus Undergoing Percutaneous Coronary Intervention: Insights From The TWILIGHT Trial Video | Slides
Dr. Duk-Woo Park Dr. Duk-Woo Park and Dr. C. Michael Gibson Discuss: Ten-year Outcomes After Drug-eluting Stents Versus Coronary Artery Bypass Grafting For Left Main Coronary Disease Video | Slides
Dr. R. Scott Wright Dr. R. Scott Wright and Dr. C Michael Gibson Discuss: Inclisiran Potently And Durably Reduces Ldl-c In A Pooled Analyses Of Phase 3 Studies Video | Slides
Dr. Mario F L Gaudino Dr. Mario F L Gaudino and Dr. C. Michael Gibson Discuss: Radial Artery Versus Saphenous Vein For Coronary Bypass Surgery At Long Term Follow-up Video | Slides
Dr. George Dangas Dr. George Dangas and Dr. C. Michael Gibson Discuss: Safety And Efficacy Of Ticagrelor Monotherapy After Complex PCI: The TWILIGHT-COMPLEX Substudy Video | Slides
Dr. William R. Hiatt Dr. William R. Hiatt and Dr. C. Michael Gibson Discuss: The Benefit And Risk Of Rivaroxaban Plus Aspirin In Patients With Peripheral Artery Disease After Lower Extremity Revascularization (ler) With And Without Concomitant Clopidogrel: A Key Subgroup Analysis From Voyager-pad Video | Slides
Dr. Giancarlo Agnelli Dr. Giancarlo Agnelli Presents: Apixaban For The Treatment Of Venous Thromboembolism Associated With Cancer: The Caravaggio Study Slides
Dr. James V. Freeman Dr. James V. Freeman and Dr. C. Michael Gibson Discuss: The NCDR Left Atrial Appendage Occlusion (LAAO) Registry: Review Of The First 3 Years Video | Slides
Dr. John H. Alexander Dr. John H. Alexander and Dr. C. Michael Gibson Discuss: How Long To Continue Aspirin After ACS/PCI In Patients With Atrial Fibrillation? Insights From Augustus Video | Slides
Dr. Michael J. Mack Dr. Michael J. Mack and Dr. C. Michael Gibson Discuss: Two-year Clinical And Echocardiographic Outcomes From The Partner 3 Low-risk Randomized Trial Video | Slides
Dr. William D. Toff Dr. William D. Toff and Dr. C. Michael Gibson Discuss: The United Kingdom Transcatheter Aortic Valve Implantation (UK TAVI) Trial Video | Slides
Dr. Basel Ramlawi Dr. Basel Ramlawi and Dr. C. Michael Gibson Discuss: Transcatheter Aortic Valve Replacement In Patients With Severe Bicuspid Aortic Valve Stenosis At Low Predicted Risk Of Mortality Video | Slides
Dr. Naveen Pereira Dr. Naveen Pereira and Dr. C. Michael Gibson Discuss: Clinical Implementation Of Clopidogrel Pharmacogenetics: The Tailor PCI Trial Video | Slides
Dr. Deepak Bhatt Dr. Deepak Bhatt and Dr. C. Michael Gibson Discuss: The Role Of Combination Antiplatelet And Anticoagulation Therapy In Diabetes And Cardiovascular Disease: Insights From The Compass Trial Video | Slides
Dr. Brian A. Ference Dr. Brian A. Ference Presents: Integrating The Effect Of Polygenic Scores, Low Density Lipoproteins And Systolic Blood Pressure On The Lifetime Risk Of Cardiovascular Disease Slides
Dr. Carolyn Lam Dr. Carolyn Lam and Dr. C. Michael Gibson Discuss: The VICTORIA (Vericiguat Global Study In Subjects With Heart Failure With Reduced Ejection Fraction) Trial Video
Dr. Paul Wayne Armstrong Dr. Paul Wayne Armstrong Presents: The VICTORIA (Vericiguat Global Study In Subjects With Heart Failure With Reduced Ejection Fraction) Trial Slides
Dr. Sigmund Silber Dr. Sigmund Silber Presents: ACC 2020 Wrap-Up in German Video