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Antiplatelet Parenteral GPiibiiia Inhibitors |
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-Summary -Trials Aggrastat (Tirofiban) Slides -Summary -Trials Eptifibatide (Integrilin) Slides -Summary -Trials |
| Abciximab (ReoPro) Slides |
Abciximab Clinical Trial Overview
-Use of ReoPro in Acute Coronary Syndrome
AIDA STEMI MRI: Cardiac MRI Substudy from a Prospective, Randomized Trial of Intracoronary Abciximab in Patients with ST-Segment Elevation Myocardial Infarction
-Study Overview by Dr. Holger Thiele (TCT 2012)
CAPTURE: C7E3 Fab Anti-Platelet Therapy in Unstable REfractory Angina
CICERO: Intracoronary Versus Intravenous Abciximab in ST-Elevation Myocardial Infarction
-Trial Results in Patients Undergoing Primary Percutaneous Coronary Intervention with Thrombus Aspiration by Dr. Youlan L. Gu (AHA 2010)
CRYSTAL AMI: Intracoronary Site-Specific Abciximab Compared to Intravenous Abciximab in Patients with Acute Myocardial Infarction Undergoing Primary Angioplasy
-A Prospective Randomized Trial of Intracoronary Site-Specific Abciximab Compared to Intravenous Abciximab in Patients with Acute Myocardial Infarction Undergoing Primary Angioplasy by Dr. Rajesh M. Dav (TCT 2010)
-Pilot Trial Results by Dr. Saihari Sadanandan (C3 Complex Intervention Meeting 2011)
E3C: EPIC, EPILOG, EPISTENT, CAPTURE
-Long-Term Mortality Follow-Up
EASY: EArly Discharge after Transradial Stenting of CoronarY Arteries
-Same-Day Home Discharge and Abciximab Bolus-Only compared to Overnight Hospitalization and Abciximab Bolus + Infusion after Trans-Radial Coronary Stenting. 12-Months Results by Dr. Oliver F. Bertrand
EPIC: Evaluation of 7E3 for the Prevention of Ischemic Complications
-Abciximab for death, MI, and revascularization in percutaneous intervention
EPILOG: Evaluation in PTCA to Improve Long-term Outcome with abciximab GP IIb/IIIa blockade
-Evaluation of PTCA to Improve Long-term Outcome by c7E3 GP IIb/IIIa receptor (abciximab) blockade
EPISTENT: EArly Discharge after Transradial Stenting of CoronarY Arteries
-Same-Day Home Discharge and Abciximab Bolus-Only compared to Overnight Hospitalization and Abciximab Bolus + Infusion after Trans-Radial Coronary Stenting. 12-Months Results by Dr. Oliver F. Bertrand
GUSTO IV ACS: Global Use of Strategies To Open Occluded Coronary Arteries in ACS
-Abciximab in NSTEMI/UA patients not planned to undergo PCI
INFUSE-AMI: A 2x2 Factorial, Multicenter, Prospective, Randomized Evaluation of Intracoronary Abciximab and Aspiration Thrombectomy in Patients Undergoing Primary PCI for Anterior STEMI.
      -Trial Overview by Dr. Gregg W. Stone (ACC 2012)
ISAR-REACT 2: The Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment 2
-Abciximab Vs. Placebo in Patients with NSTEMI undergoing PCI Aftrer Pretreatment with Clopidogrel by Dr. M. Seyfarth
MULTI-STRATEGY Trial: MULTIcentre evaluation of Single high-dose bolus TiRofiban versus Abciximab with sirolimus eluting sTEnt or bare metal stent in acute myocardial infarction studY
-Evaluation of single high-bolus dose tirofiban Vs. abciximab and SES Vs. BMS in acute MI by Dr. Marco Valgimigli
RELAx-AMI: Randomized Early versus Late AbciXimab in Acute Myocardial Infarction treated with primary coronary intervention
-Early versus Late Abciximab in AMI treated with primary coronary intervention by Dr. Mauro Maioli
SCAAR: Non-randomized Comparison from SCAAR of Eptifibatide of Abciximab in Primary PCI for STEMI
-Results from the SCAAR (Swedish Coronary Angiography and Angioplasty Registry) by Dr. Axel Akerblom
TARGET: Do Tirofiban And ReoPro Give Similar Efficacy Outcomes Trial
| Aggrastat (Tirofiban) Slides |
APEX: Assessment of Pexelizumab in Acute Myocardial Infarction
-New Treatment Advances in Acute Coronary Syndrome
Case Studies in the Management of ACS with GP IIb/IIIa Inhibitors
Empiric Management of ACS with GP IIb/IIIa Platelet Receptor Blockers
-Continuing Medical Education Activity by Drs. Christopher P. Cannon and Alan C. Yeung
MULTI-STRATEGY Trial: MULTIcentre evaluation of Single high-dose bolus TiRofiban versus Abciximab with sirolimus eluting sTEnt or bare metal stent in acute myocardial infarction studY
-Study Design by Dr. Marco Valgimigli
STRATEGY Trial: sTEnt versus abciximab and bare metal stent in acute mYocardial infarction
-Three-year clinical follow-up after sirolimus-eluting versus bare metal stent implantation assisted by systematic GP IIb/IIIa infusion in patients with MI by Dr. Marco Valgimigli
Tirofiban Meta-Analysis
-30-Day Results by Dr. Marco Valgimigli
Understanding Concepts of Equivalence and Non-inferiority Trials
-Understanding Concepts of Equivalence and Non-inferiority Trials by Dr. C. Michael Gibson
MULTI-STRATEGY Trial: MULTIcentre evaluation of Single high-dose bolus TiRofiban versus Abciximab with sirolimus eluting sTEnt or bare metal stent in acute myocardial infarction studY
-Study Design by Dr. Marco Valgimigli
PRISM-Plus: The Platelet Receptor Inhibition for Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms
-Tirofiban and heparin in the treatment of unstable angina and non-Q-wave myocardial infarction
PRISM/RESTORE
-Effect of tirofiban in patients undergoing coronary interventions
TACTICS-TIMI 18: Treat Angina with Aggrastat and Determine Cost of Therapy with an Invasive or Conservative Strategy
TOPSTAR: Effect of Additional Temporary Glycoprotein IIb-IIIa Receptor Inhibition on Troponin Release in Elective Percutaneous Coronary Interventions After Pretreatment With Aspirin and Clopidogrel
| Eptifibatide (Integrilin) Slides |
Safety and Efficacy of Adjusted-Dose Eptifibatide in Patients with Acute Coronary Syndromes and Reduced Renal Function:
-Overview by Dr. Chiara Melloni
Early ACS: Early Glycoprotein IIb/IIIa Inhibition in Non-ST-segment Elevation Acute Coronary Syndrome
-An Analysis from the Early ACS Trial by Dr. Tracy Wang (ACC 2010)
ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia Trial
SCAAR: Non-randomized Comparison from SCAAR of Eptifibatide of Abciximab in Primary PCI for STEMI
-Results from the SCAAR (Swedish Coronary Angiography and Angioplasty Registry) by Dr. Axel Akerblom
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