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Congestive Heart Failure

Summary Slides
ACE Inhibition
Other Pharmacotherapy
 Summary Slides

Acute Heart Failure in Apical Ballooning Syndrome (Takotsubo/Stress Cardiomyopathy): Clinical Correlates and Mayo Clinic Risk Score

      -Overview by Dr. Abhiram Prasad


ADHERE: Acute Decompensated Heart Failure National Registry

      -Admission B-Type Natriuretic Peptide Levels and In-Hospital Mortality in Acute Decompensated Heart Failure by Dr. Gregg C. Fonarow


ASCEND-HF: Acute Study of Clinical Effectivenes of Nesiritide in Decompensated Heart Failure

      -Historical Perspective, Implications for Patients Failure Trial by Dr. Adrian Hernandez (AHA 2010)

BACH Multinational Trial: Biomarkers in the Assessment of Congestive Heart Failure

      -Mid-Regional pro-Adrenomedullin (MR-proADM) vs BNP NT-proBNP as Prognosticator in Heart Failure Patients by Dr. Stefan D. Anker

CARRESS-HF: Cardiorenal Rescue Study in Decompensated Heart Failure

      -Trial Results by Dr. Bradley Bart (AHA 2012)


HOOPS: A Prospective Cluster Randomized Trial of Pharmacist Intervention to Prevent Hospitalization and Death in Patients with Heart Failure

      -Trial Overview by Dr. Richard Lowrie (AHA 2011)

Epidemiology of CHF

      -Epidemiology of CHF: Gender, age, readmission and survival in CHF

HF-ACTION Substudy: Heart Failure–A Randomized Controlled Trial Investigating Outcomes Of Exercise Training

      -Effect of Exercise Training on Health Related Quality of Life in Patients with Chronic Heart Failure by Dr. Kathryn Flynn and Dr. Ileana Pina

PEACE Trial: Prevention of Events with Angiotensin Converting Enzyme Inhibition

      -Prognostic Value of B-Type Natriuretic Peptides in Patients with Stable Coronary Artery Disease by Professor Torbjorn Omland


PROTECT: Benefits of Natriuretic Peptide Guided Heart Failure Therapy for Patients With Chronic Left Ventricular Systolic Dysfunction

      -Results of the Pro-BNP Outpatient Tailored Chronic Heart Failure Therapy Study by Dr. James Januzzi (AHA 2010)

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 ACE Inhibition

CAMELOT: Comparison of Amlodipine vs. Enalapril to Limit Occurrences of Thrombosis

      -Trial Overview by Dr. Steven Nissen

CHARM: Candesartan Cilexitil [Atacand™] in Heart Failure Assessment of Reduction Mortality and Morbidity

      -Trial Overview (European Society of Cardiology 2003)

      -Red Cell distribution Width as a Novel Prognostic Marker in Heart Failure: Data from the CHARM Program and the DUKE Databank

CONSENSUS 1: Coorperative North Scandinavian Enalapril Survival Study

      -Enalapril vs. placebo for 6-month mortality in severe heart failure after MI

ELITE II: Losartan Heart Failure Survival Study

      -Effects of Losartan Compared with Captopril on Mortality in Patients with Symptomatic Heart Failure by Dr. Bertram Pitt, et al.

EUROPA: European Trial On Reduction Of Cardiac Events With Perindopril In Stable Coronary Artery Disease

      -Treatment with perindopril vs placebo on cardiovascular events in patients with stable coronary artery disease (European Society of Cardiology 2003)

HOPE: Heart Outcomes Prevention Evaluation

      -Effect of ACE Inhibitor, Ramipril, on Death from Cardiovascular Causes, Myocardial Infarction, and Stroke in High-Risk Patients

LIFE: Losartan Intervention for Endpoint Reduction in Hypertension Study

      -Trial Overview by Dr. Björn Dahlöf

PEACE: Prevention of Events with Angiotensin Converting Enzyme Inhibition

      -Trial Overview by Dr. Mark Pheffer (AHA 2004)

SOLVD: Studies Of Left Ventricular Dysfunction

      -Enalapril vs Placebo in Patients with Reduced Left Ventricular Function and Congestive Heart Failure when Added to ACE Inhibitors

VALIANT: Valsartan in Acute Myocardial Infarction Trial

      -Effect of valsartan, captopril, and the combination of the two on mortality in patients with myocardial infarction complicated by left ventricular systolic dysfunction, heart failure, or both by Dr. Marc A. Pfeffer (AHA 2003)

VHEFT 1: The Effects Of Vasodilator Therapy On Mortality In Chronic Congestive Heart Failure

      -Effects of Prazosin, or combination of Hydralazine and Isosorbide dinitrate in symptomatic patients with heart failure and left ventricular dysfunction on digitalis and diuretics

VHEFT 2: Efficacy And Outcome With Felodipine In Heart Failure

      -Enalapril vs. hydralazine/nitrates for mortality in moderate heart failure

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 Other Pharmacotherapy

A-Heft: African-American Heart Failure

      -Impact of ISDN-hydralazine on mortality and morbidity of African-American patients with Heart Failure by Anne L. Taylor (AHA 2004)

ACTION: A Coronary Disease Trial Investigating Outcome with Nifedipine GITS (Gastrointestinal Therapeutic System)

      -Nifedipine in Treatment of Hypertension by Philip A. Poole-Wilson

CIBIS III: Cardiac Insufficiency Bisoprolol Study III

      -Bisoprolol in CHF by Dr. Ronnie Willenheimer

COMET: Carvedilol Or Metoprolol European Trial

      -Mortality and morbidity between the multiple adrenergic inhibitor carvedilol and the beta-1-selective agent metoprolol

ESSENTIAL: The Studies Of Oral Enoximone Therapy In Advanced Heart Failure

      -Safety and efficacy of low-dose enoximone therapy among patients with advanced chronic heart failure already receiving optimal conventional therapy by Dr. Marco Metra

EVEREST: Efficacy of Vasopressin antagonism in hEart failuRE: outcome Study with Tolvaptan

      -Trial Outcome by Dr. Marvin A. Konstam, et al.

FUSION II: Follow-Up Serial Infusions of Nesiritide for the Management of Patients With Heart Failure

      -Trial Results by Dr. Clyde W. Yancy (ACC 2007)

I-PRESERVE Trial: Irbesartan in Heart Failure with Preserved EF

      -Trial Overview by Drs. Peter Carson and Barry Massie

SURVIVE-W: Survival of Patients with Acute Heart Failure in Need of Intravenous Inotropic Support

      -Survival of Patients with Acute Heart Failure in Need of Intravenous Inotropic Support by Dr. Alexandre Mebazaa (AHA 2005)

TRIUMPH: Tilarginine Acetate Injection in a Randomized International Study in Unstable Acute Myocardial Infarction Patients with Cardiogenic Shock

      -Trial Overview by Dr. Judith S. Hochman

VERITAS: Value of Endothelin Receptor Inhibition with Tezosentan in Acute Heart Failure Studies

      -Trial Overview by Dr. John J. V. McMurray (ACC 2004)

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3CPO Trial:

      -Efficacy Non-Invasive Ventilation in Patients with Acute Cardiogenic Pulmonary Edema by Dr. David Newby

ACORN: Assessment Of A Cardiac Support Device (CSD) In Patients With Heart Failure

      -Trial Overview by Dr. D.L. Mann (AHA 2004)

BLOCK HF: Biventricular Versus Right Ventricular Pacing in Patients with Left Ventricular Dysfunction and Atrioventricular Block

     -Preliminary Results by Dr. Anne B. Curtis et al. (AHA 2012)

CANPAP: Continuous Positive Airway Pressure for Heart Failure Patients with Central Sleep Apnea

      -Trial Overview by Dr. T. Douglas Bradley (ACC 2005)

CARE-HF: Cardiac Resynchronization Heart Failure Study

      -Trial Overview by Dr. John G. Cleland (ACC 2005)

COMPASS-CHF: Chronicle Offers Management to Patients with Advanced Signs and Symptoms of Heart Failure

      -Trial Overview by Dr. Robert C. Bourge (ACC 2005)

PEECH: Prospective Evaluation of EECP in Congestive Heart Failure

      -Trial Overview by Dr. Arthur M. Feldman (ACC 2005)

Percutaneous Cell Transplantation of Autologous Skeletal Myoblast

      -Myocardial Repair by Percutaneous Cell Transplantation of Autologous Skeletal Myoblast as a Stand Alone Procedure in post-MI CHF Patients by Dr. Patrick W. Serruys

PROSPECT Study: Predictors of Response to CRT

      -Trial Overview by Dr. Cecilia Linde

Total Artificial Heart:

      -An Evolving Role in the Management of End-Stage Heart Failure by Dr. Marvin J. Slepian


      -VentrAssist U.S. Pivotal Bridge to Cardiac Transplantation Trial by Dr. Andrew Boyle

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