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Antiplatelet Therapy

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Pathophysiology & Summary Slides
Oral
Parenteral (IV)
 Pathophysiology & Summary Slides 

Antiplatelet Therapy in ACS and PCI

      -Challenges and Future Directions by Dr. Stephen D. Wiviott (2007)

ARCTIC: Antiplatelet Treatment Versus a Common Antiplatelet Treatment for DES Implantation

    -A Double Randomization of a Monitoring Adjusted Antiplatelet Treatment Versus a Common Antiplatelet Treatment for DES Implantation, and Interruption Versus Continuation of Double Antiplatelet Therapy by Dr. Jean-Philippe Collet (TCT 2010)

    -Trial Overview by Dr. Gilles Montalescot (AHA 2012)

 

CILON-T: Randomized Prospective Trial of Dual vs. Triple Antiplatelet Therapy After DES Implantation

      -Trial Overview by Dr. Hyo-Soo Kim (CRT 2011)

CLEAR PLATELETS Ib

      -A Mechanistic Link Between High Platelet Reactivity, Inflammation Marker Release and Myonecrosis in Patients Undergoing Stenting by Dr. Paul Gurbel, et al.

   

GRAVITAS: Platelet Reactivity on Clopidogrel Therapy and CV Outcomes after PCI

      -Trial Results by Dr. Matthew Price (AHA 2010)

      -A Time-Dependent Pharmacodynamic Analysis of the GRAVITAS trial by Dr. Matthew Price (TCT 2011)

 

Identifying Patients at Risk for Premature Discontinuation of Thienopyridine After Coronary Stent Implantation:

      -Overview by Dr. Alexandre Quadros (CRT 2011)

 

Impact of Platelet Reactivity When On-treatment With Clopidogrel on Mortality, MI or Stent Thrombosis After PCI: A Collaborative Meta-Analysis of Individual Patient Data

      -Trial Results by Dr. Somjot Brar and Dr. George D. Dangas (ACC 2011)

 

PARIS: A Large-Scale, Prospective, Multicenter Registry Studying the Patterns of and Reasons for Non-Adherence to Antiplatelet Agents in Stented Patients

      -Study Overview by Dr. Roxana Mehran (TCT 2011)

 

Platelet Function Testing and Clinical Events: Baylor Perspective: Review of the Evidence and Are They Prime for Incorporation in Clinical Practice?

      -Overview by Dr. Mohan Sathyamoorthy (C3 Complex Intervention Meeting 2011)

 

Prevalence, Predictors, and Long-Term Prognosis of Premature Discontinuation of Oral Antiplatelet Therapy After Drug Eluting Stent Implantation:

      -Trial Overview by Dr. Dominick Angiolillo (CRT 2011)

 

PRODIGY: Prolonging Dual Antiplatelet Treatment After Grading Stent-Induced Intimal Hyperplasia Study

      -Study Overview by Dr. M. Valgimigli (ESC 2011)

 

RESET: A New Strategy for Discontinuation of Dual Antiplatelet Therapy: Real Safety and Efficacy of 3-Month Dual Antiplatelet Therapy Following Zotarolimus-Eluting Stent Implantation

      -Trial Overview by Dr. Myeong-Ki Hong (TCT 2012)

TRILOGY ACS Platelet Function Sub-study: First Large-Scale Platelet Function Evaluation in an Acute Coronary Syndromes Trial

      -Trial Overview by Dr. Paul Gurbel and Dr. Magnus Ohman (AHA 2012)

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 Oral

Antiplatelets:

      -Aspirin

      -Clopidogrel

      -Elinogrel

      -Prasugrel

      -Thrombin Receptor Antagonism (TRA)

      -Ticagrelor

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 Parenteral (IV)

Antiplatelets

      -Elinogrel

      -Glycoprotein 2b3a Inhibitors

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